Gen. Nathan Bedord Forrest III, the great grandson of the Civil War (and Ku Klux Klan) leader was killed in a bombing raid against the German submarine base at Kiel on July 13, 1943. Some say he was the first American general to die in combat in World War II but that’s parsing things.
Brigadier General Guy O. Fort of the 81st Philippine Division was captured, tortured and executed by the Japanese in January 1942, while Brigadier Gen. Charles L. Keerans Jr., assistant division commander of the 82nd Airborne Division, went missing in action on June 11, 1943 due to a friendly fire incident and was later declared dead.